About megatomi.com
About megatomi.com
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Our new Obvious+ tissue clearing procedure is the only real approach that delipidates samples without having change in morphology and with minimum effect on structural integrity.
Megatome is actually a vibrating microtome intended to part a wide number of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome enables large-throughput tissue sectioning with uniform surface area profile, and negligible tissue damage and information loss.
Antibodies may perhaps choose months to diffuse as a result of only some millimeters of tissue, which has a steep labeling gradient from area to Main.
Megatome is suitable for precision: the blade vibrates at the next frequency and bigger amplitude array than other microtomes, and contains a one of a kind deflection Manage mechanism.
SE uses a rotational electric powered industry to disperse remarkably electromobile molecules (for example antibodies or surfactant micelles) through a porous sample without having damaging electrically charged buildings throughout the tissue. This allows two-four working day clearing of intact organs,
Our preformulated EasyIndex solution raises and homogenize the refractive index of delipidated tissue samples, rendering them absolutely clear. This permits light penetration into the sample and makes sure the acquisition of substantial-resolution, in-target image details.
Megatome can be a novel microtome that allows for top-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with nominal tissue harm and knowledge reduction.
eFLASH is usually a quick tissue labeling method which allows for uniform complete-organ staining in 20 rounds of labeling.
Thoroughly delipidate entire mouse brains or comparably sized samples in only one day with SmartBatch+, or in a single week with our passive clearing kit.
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Either obtain a launch or make a distribution zip as outlined over. Unzip the archive into a wished-for place.
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Our novel Defend tissue preservation procedure sorts intramolecular bonds using polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.